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Applications Systems Analysis & Programming Manager

Ann Arbor, MI
Full-Time

Job Description

How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

The Applications Systems Analysis & Programming Manager will support a highly interactive research team in the Center for Statistical Genetics (CSG) at the University of Michigan School of Public Health. The group is involved in cutting-edge genetics research, studying genetic variation in humans, with a focus on understanding how genetic variation contributes to the risk of complex disorders such as diabetes, heart disease, late-onset blindness and psychiatric illness. The group participates in all aspects of the processing and analysis of genetic data, ranging from the development of data processing scripts and pipelines to the development, distribution, and maintenance of free software for the analysis of genetic data. This is an opportunity to work in a challenging and rewarding research area that constantly poses new technical and computational problems.

We are analyzing some of the largest genetic datasets in the world, totaling petabytes of data and often requiring the deployment of 10,000s of cores in each analysis. This position will focus on the development and deployment of user-facing web applications that automate research analyses, as well as transitioning local processes and applications to secure cloud environments. You must have cloud computing experience and should also have experience with full-stack web application development. This position will report to the Principal Investigator.

Why Work at Michigan?

In addition to a career filled with purpose and opportunity, The University of Michigan offers a comprehensive benefits package to help you stay well, protect yourself and your family and plan for a secure future. Benefits include:

  • Generous time off, including family leave
  • A retirement plan that provides two-for-one matching contributions with immediate vesting
  • Many choices for comprehensive health insurance, dental, vision
  • Life insurance
  • Long-term disability coverage
  • Flexible spending accounts for healthcare and dependent care expenses

Responsibilities*

  • Supervises scientific programming in the group, notably overseeing the development and maintenance of scientific applications. These applications include critical tools under active development in the group, including genotype imputation server software and a genome-wide association server. (20%)
  • Supervises and comments on association analyses of multi-omic data, including methylation, proteomics and RNAseq data. Ensures that summary results from this work are incorporated into scientific application developed by the group. (10%)
  • Plans, conducts and coordinates the application of state-of-the-art information processing techniques to existing and future needs. Performs complex systems analysis and programming tasks requiring advanced techniques on the forefront of technology. Provides leadership in specific areas of IT responsibility. (20%)
  • Provides analytical support in the conceptualization, development and implementation of interlinked systems and programs. Coordinates the interfaces between major systems and programs. This includes designing and implementing an optimal infrastructure, back-end and front-end layers for new software for genetic data analysis and visualization, which would satisfy all efficiency, security and reliability requirements. Provides technical advice and consultation on complex analysis and programming applications. (15%)
  • Designs genetic analyses and data processing pipelines and tailors visualization for large scale genetic datasets. This includes work in close collaboration with field experts on (1) scaling existing analysis tools to massive genetic datasets; (2) developing and managing automated analysis pipelines for on-premise and cloud computing clusters; (3) developing web-based tools for data visualization and sharing. (20%)
  • Performs complex systems analysis and programming tasks requiring advanced techniques. (10%)
  • Debugs malfunctions, problem solves, and modifies programs, as needed. (5%)

    Required Qualifications*

    • Bachelor's degree in Computer Science or related field, or equivalent experience. 
    • 7-10 years of systems analysis/programming in a research environment.
    • Experience in Statistical Genetics, scientific computing and data visualization is required.
    • Programming languages: Python, C/C++, Java
    • Strong skills in Linux shell (e.g. bash) scripting
    • Strong knowledge of data structures and algorithms
    • Experience with SQL and noSQL databases
    • Experience in front-end web-development with JavaScript and frameworks such as Vue.js, AngularJS, and React.
    • Experience with cloud computing solutions on Google Cloud and/or Amazon Web Services would be an advantage
    • Familiarity with job schedulers (e.g. SLURM or Torque/PBS) and workflows (e.g. Snakemake, Nextflow, or CWL) would be an advantage.
    • Prior experience in a FISMA-compliant environment. 

      Work Locations

      This position is primarily on-site and requires residence in commuting distance to the Ann Arbor campus.

      Modes of Work

      Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

      Underfill Statement

      This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

      Background Screening

      The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks.  Background checks are performed in compliance with the Fair Credit Reporting Act.

      Application Deadline

      Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

      U-M EEO Statement

      The University of Michigan is an equal employment opportunity employer.

      PDN-a072491b-f126-40d9-9315-8d4b5a5bea2f

How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

The Applications Systems Analysis & Programming Manager will support a highly interactive research team in the Center for Statistical Genetics (CSG) at the University of Michigan School of Public Health. The group is involved in cutting-edge genetics research, studying genetic variation in humans, with a focus on understanding how genetic variation contributes to the risk of complex disorders such as diabetes, heart disease, late-onset blindness and psychiatric illness. The group participates in all aspects of the processing and analysis of genetic data, ranging from the development of data processing scripts and pipelines to the development, distribution, and maintenance of free software for the analysis of genetic data. This is an opportunity to work in a challenging and rewarding research area that constantly poses new technical and computational problems.

We are analyzing some of the largest genetic datasets in the world, totaling petabytes of data and often requiring the deployment of 10,000s of cores in each analysis. This position will focus on the development and deployment of user-facing web applications that automate research analyses, as well as transitioning local processes and applications to secure cloud environments. You must have cloud computing experience and should also have experience with full-stack web application development. This position will report to the Principal Investigator.

Why Work at Michigan?

In addition to a career filled with purpose and opportunity, The University of Michigan offers a comprehensive benefits package to help you stay well, protect yourself and your family and plan for a secure future. Benefits include:

  • Generous time off, including family leave
  • A retirement plan that provides two-for-one matching contributions with immediate vesting
  • Many choices for comprehensive health insurance, dental, vision
  • Life insurance
  • Long-term disability coverage
  • Flexible spending accounts for healthcare and dependent care expenses

Responsibilities*

  • Supervises scientific programming in the group, notably overseeing the development and maintenance of scientific applications. These applications include critical tools under active development in the group, including genotype imputation server software and a genome-wide association server. (20%)
  • Supervises and comments on association analyses of multi-omic data, including methylation, proteomics and RNAseq data. Ensures that summary results from this work are incorporated into scientific application developed by the group. (10%)
  • Plans, conducts and coordinates the application of state-of-the-art information processing techniques to existing and future needs. Performs complex systems analysis and programming tasks requiring advanced techniques on the forefront of technology. Provides leadership in specific areas of IT responsibility. (20%)
  • Provides analytical support in the conceptualization, development and implementation of interlinked systems and programs. Coordinates the interfaces between major systems and programs. This includes designing and implementing an optimal infrastructure, back-end and front-end layers for new software for genetic data analysis and visualization, which would satisfy all efficiency, security and reliability requirements. Provides technical advice and consultation on complex analysis and programming applications. (15%)
  • Designs genetic analyses and data processing pipelines and tailors visualization for large scale genetic datasets. This includes work in close collaboration with field experts on (1) scaling existing analysis tools to massive genetic datasets; (2) developing and managing automated analysis pipelines for on-premise and cloud computing clusters; (3) developing web-based tools for data visualization and sharing. (20%)
  • Performs complex systems analysis and programming tasks requiring advanced techniques. (10%)
  • Debugs malfunctions, problem solves, and modifies programs, as needed. (5%)

    Required Qualifications*

    • Bachelor's degree in Computer Science or related field, or equivalent experience. 
    • 7-10 years of systems analysis/programming in a research environment.
    • Experience in Statistical Genetics, scientific computing and data visualization is required.
    • Programming languages: Python, C/C++, Java
    • Strong skills in Linux shell (e.g. bash) scripting
    • Strong knowledge of data structures and algorithms
    • Experience with SQL and noSQL databases
    • Experience in front-end web-development with JavaScript and frameworks such as Vue.js, AngularJS, and React.
    • Experience with cloud computing solutions on Google Cloud and/or Amazon Web Services would be an advantage
    • Familiarity with job schedulers (e.g. SLURM or Torque/PBS) and workflows (e.g. Snakemake, Nextflow, or CWL) would be an advantage.
    • Prior experience in a FISMA-compliant environment. 

      Work Locations

      This position is primarily on-site and requires residence in commuting distance to the Ann Arbor campus.

      Modes of Work

      Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

      Underfill Statement

      This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

      Background Screening

      The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks.  Background checks are performed in compliance with the Fair Credit Reporting Act.

      Application Deadline

      Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

      U-M EEO Statement

      The University of Michigan is an equal employment opportunity employer.

      PDN-a072491b-f126-40d9-9315-8d4b5a5bea2f

About University of Michigan

Why Work at Michigan?

Being part of something greater, of serving a larger mission of discovery and care — that's the heart of what drives people to work at Michigan. In some way, great or small, every person here helps to advance this world-class institution. It's adding a purpose to your profession. Work at Michigan and become a victor for the greater good.

 

Workplace Culture

The University of Michigan is committed to establishing, supporting and maintaining a culture where all members of the U-M community feel safe and supported.


Our Values

  • Values guide our choices and actions. From how we hire and promote, make decisions, educate, conduct research, provide care, and treat one another. We strive to ensure the following values reflect who we are and what we stand for.
  • Integrity - We act with honesty and take responsibility for our actions.
  • Respect - We act in a way that acknowledges the humanity and contributions of each individual.
  • Inclusion- We create an environment where all can participate, are invited to contribute, and have a sense of belonging.
  • Equity - We create conditions that provide everyone an opportunity to thrive.
  • Diversity - We welcome, acknowledge and appreciate our similarities and differences.
  • Innovation - We promote creativity and curiosity to tackle challenges and inspire new ideas.

 

More about Working at U-M

  • Our commitment to campus culture
  • Our commitment to faculty and staff well-being
  • Our commitment to employee engagement

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Apply For This Job
Applications Systems Analysis & Programming Manager
University of Michigan
Ann Arbor, MI
Nov 26, 2025
Full-time
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